In these respects, the marrow fat of exercising obese mice looked virtually identical to the marrow fat of lean mice, even those that exercised. Or, because both fat and bone cells come from parent cells known as mesenchymal stem cells, it could be that exercise somehow stimulates these stem cells to churn out more bone cells and less fat cells. Styner's work also offers fundamental insights on how marrow fat forms and the impact it has on bone health. Predictably, the obese mice started with more fat cells and larger fat cells in their marrow. Using MRI to assess marrow fat eliminates the need for the toxic tracer and allows highly detailed imaging of living organisms.
Exercise helps burn bone fat

Exercising burns the fat found within bone marrow and this process improves bone quality in a matter of weeks, says a study. Although research in mice is not directly translatable to the human condition, the kinds of stem cells that produce bone and fat in mice are the same kind that produce bone and fat in humans. "In just a very short period of time, we saw that running was building bone significantly in mice," Styner said. The study, published in the Journal of Bone and Mineral Research, also suggests that obese individuals - who often have worse bone quality - may derive even greater bone health benefits from exercising than their lean counterparts. Our studies of bone biomechanics show that the quality and the strength of the bone is significantly increased with exercise and even more so in the obese exercisers," Styner said.
collected by :Lucy William



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